Self-organization and regulation of intrinsically disordered proteins with folded N-termini

Here we hypothesize that some proteins use their structured N-terminal domains (SNTDs) to organize the remaining protein chain by means of intramolecular interactions, so generating partially condensed proteins. This model has several attractive features: as the nascent protein chain emerges from th...

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Bibliographic Details
Main Authors: Simister, P, Schaper, F, O'Reilly, N, McGowan, S, Feller, S
Format: Journal article
Language:English
Published: Public Library of Science 2011