Precise somatotopic thalamocortical axon guidance depends on LPA-mediated PRG-2/radixin signaling

Precise somatotopic thalamocortical axon guidance depends on LPA-mediated PRG-2/radixin signaling

Precise connection of thalamic barreloids with their corresponding cortical barrels is critical for processing of vibrissal sensory information. Here, we show that PRG-2, a phospholipid-interacting molecule, is important for thalamocortical axon guidance. Developing thalamocortical fibers both in PR...

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Detalhes bibliográficos
Principais autores: Cheng, J, Sahani, S, Hausrat, T, Yang, J, Ji, H, Schmarowski, N, Endle, H, Liu, X, Li, Y, Böttche, R, Radyushkin, K, Maric, H, Hoerder-Suabedissen, A, Molnár, Z, Prouvot, P, Trimbuch, T, Ninnemann, O, Huai, J, Fan, W, Visentin, B, Sabbadini, R, Strømgaard, K, Stroh, A, Luhmann, H, Kneussel, M, Nitsch, R, Vogt, J
Formato: Journal article
Idioma:English
Publicado em: Cell Press 2016

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