Decreased hippocampal expression of the susceptibility gene PPP3CC and other calcineurin subunits in schizophrenia.

BACKGROUND: Calcineurin (CaN) is a phosphatase involved in synaptic plasticity. A haplotype of the PPP3CC gene, which encodes the gamma isoform of the catalytic subunit (CaN A), has been associated with schizophrenia. However, the distribution of CaN A gamma is not established, nor whether its expr...

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Bibliographic Details
Main Authors: Eastwood, S, Burnet, P, Harrison, P
Format: Journal article
Language:English
Published: 2005