The glycosylphosphatidylinositol-PLC in Trypanosoma brucei forms a linear array on the exterior of the flagellar membrane before and after activation

Bloodstream forms of Trypanosoma brucei contain a glycosylphosphatidylinositol-specific phospholipase C (GPI-PLC) that cleaves the GPI-anchor of the variable surface glycoprotein (VSG). Its location in trypanosomes has been controversial. Here, using confocal microscopy and surface labelling techniq...

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Bibliographic Details
Main Authors: Hanrahan, O, Webb, H, O'Byrne, R, Brabazon, E, Treumann, A, Sunter, JD, Carrington, M, Voorheis, HP
Format: Journal article
Language:English
Published: Public Library of Science 2009