A KMT2A-AFF1 gene regulatory network highlights the role of core transcription factors and reveals the regulatory logic of key downstream target genes

Regulatory interactions mediated by transcription factors (TFs) make up complex networks that control cellular behavior. Fully understanding these gene regulatory networks (GRNs) offers greater insight into the consequences of disease-causing perturbations than can be achieved by studying single TF...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Harman, JR, Thorne, R, Jamilly, M, Tapia, M, Crump, NT, Rice, S, Beveridge, R, Morrissey, E, de Bruijn, MFTR, Roberts, I, Roy, A, Fulga, TA, Milne, T
פורמט: Journal article
שפה:English
יצא לאור: Cold Spring Harbor Laboratory Press 2021