Direct observation of the influence of cardiolipin and antibiotics on lipid II binding to MurJ

Translocation of lipid II across cytoplasmic membrane is essential in peptidoglycan biogenesis. While most steps are understood, identifying the lipid II flippase has yielded conflicting results and the lipid II binding properties of two candidate flippases, MurJ and FtsW, remain largely unknown. He...

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Bibliographic Details
Main Authors: Bolla, J, Sauer, J, Wu, D, Mehmood, S, Allison, T, Robinson, C
Format: Journal article
Published: Nature Publishing Group 2018