Comparison of fine-scale recombination rates in humans and chimpanzees.

We compared fine-scale recombination rates at orthologous loci in humans and chimpanzees by analyzing polymorphism data in both species. Strong statistical evidence for hotspots of recombination was obtained in both species. Despite approximately 99% identity at the level of DNA sequence, however, r...

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Bibliographic Details
Main Authors: Winckler, W, Myers, S, Richter, D, Onofrio, R, McDonald, G, Bontrop, R, Mcvean, G, Gabriel, S, Reich, D, Donnelly, P, Altshuler, D
Format: Journal article
Language:English
Published: 2005