Cyclic Boronates Inhibit All Classes of β-Lactamase.
β-Lactamase-mediated resistance is a growing threat to the continued use of β-lactam antibiotics. The use of the β-lactam-based serine-β-lactamase (SBL) inhibitors clavulanic acid, sulbactam, tazobactam, and, more recently, the non-β-lactam inhibitor avibactam has extended the utility of β-lactams a...
Autors principals: | Cahill, S, Cain, R, Wang, D, Lohans, C, Wareham, D, Oswin, H, Mohammed, J, Spencer, J, Fishwick, C, McDonough, M, Schofield, C, Brem, J |
---|---|
Format: | Journal article |
Idioma: | English |
Publicat: |
American Society for Microbiology
2017
|
Ítems similars
-
Studies on the inhibition of AmpC and other β-lactamases by cyclic boronates
per: Cahill, S, et al.
Publicat: (2019) -
Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates
per: Brem, J, et al.
Publicat: (2016) -
Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition
per: Tooke, C, et al.
Publicat: (2020) -
13 C-Carbamylation as a mechanistic probe for the inhibition of class D β-lactamases by avibactam and halide ions
per: Lohans, C, et al.
Publicat: (2017) -
Broad spectrum β-lactamase inhibition by a thioether substituted bicyclic boronate
per: Parkova, A, et al.
Publicat: (2019)