Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn’s disease

Previous work has shown that the gene DMBT1, which encodes a large secreted epithelial glycoprotein known as salivary agglutinin, gp340, hensin or muclin, is an innate immune defence protein that binds bacteria. A deletion variant of DMBT1 has been previously associated with Crohn’s disease, and a D...

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Bibliographic Details
Main Authors: Polley, S, Prescott, N, Nimmo, E, Veal, C, Vind, I, Munkholm, P, Fode, P, Mansfield, J, Skyt Andersen, P, Satsangi, J, G Mathew, C, Hollox, E
Format: Journal article
Published: Springer Nature 2016