Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.

BACKGROUND: HLA class-I alleles differ in their ability to control HIV replication through cell-mediated immune responses. No consistent associations have been found between the breadth of Cytotoxic T Lymphocytes (CTL) responses and the control of HIV-1, and it is unknown whether the size or distri...

Full description

Bibliographic Details
Main Authors: Rolland, M, Heckerman, D, Deng, W, Rousseau, C, Coovadia, H, Bishop, K, Goulder, P, Walker, B, Brander, C, Mullins, J
Format: Journal article
Language:English
Published: 2008