Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.

Broad and Gag-biased HIV-1 epitope repertoires are associated with lower viral loads.

BACKGROUND: HLA class-I alleles differ in their ability to control HIV replication through cell-mediated immune responses. No consistent associations have been found between the breadth of Cytotoxic T Lymphocytes (CTL) responses and the control of HIV-1, and it is unknown whether the size or distri...

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Detalles Bibliográficos
Main Authors: Rolland, M, Heckerman, D, Deng, W, Rousseau, C, Coovadia, H, Bishop, K, Goulder, P, Walker, B, Brander, C, Mullins, J
Formato: Journal article
Idioma:English
Publicado: 2008

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