Jam-a is highly expressed on human hematopoietic repopulating cells and associates with the key hematopoietic chemokine receptor cxcr4.

Jam-a is highly expressed on human hematopoietic repopulating cells and associates with the key hematopoietic chemokine receptor cxcr4.

<p>Hematopoietic stem/progenitor cells (HSPCs) reside in specialized bone marrow microenvironmental niches, with vascular elements (endothelial/mesenchymal stromal cells) and CXCR4-CXCL12 interactions playing particularly important roles for HSPC entry, retention and maintenance. The functiona...

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Bibliographic Details
Main Authors: Watt, S, Chang, C, Hale, S, Cox, C, Blair, A, Kronsteiner, B, Grabowska, R, Zhang, Y, Cook, D, Khoo, C, Schrader, J, Buglass Kabuga, S, Martin-Rendon, E
Format: Journal article
Published: Wiley 2016

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