Vessel co-option in primary human tumors and metastases: an obstacle to effective anti-angiogenic treatment?

Angiogenesis has been regarded as essential for tumor growth and progression. Studies of many human tumors, however, suggest that their microcirculation may be provided by nonsprouting vessels and that a variety of tumors can grow and metastasize without angiogenesis. Vessel co-option, where tumor c...

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Bibliographic Details
Main Authors: Donnem, T, Hu, J, Ferguson, M, Adighibe, O, Snell, C, Harris, A, Gatter, K, Pezzella, F
Format: Journal article
Language:English
Published: 2013