The TREX2 3'-->5' exonuclease physically interacts with DNA polymerase delta and increases its accuracy.
Proofreading function by the 3'-->5' exonuclease of DNA polymerase delta (pol delta) is consistent with the observation that delta efficiency of the associated exonuclease can lead to a strong mutation phenotype, high error rates during DNA replication, and ultimately cancer. We hav...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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