The effect of genome-wide association scan quality control on imputation outcome for common variants.

The effect of genome-wide association scan quality control on imputation outcome for common variants.

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Imputation is an extremely valuable tool in conducting and synthesising genome-wide association studies (GWASs). Directly typed SNP quality control (QC) is thought to affect imputation quality. It is, therefore, common practise to use quality-controlled (QCed) data as an input for imputing genotypes...

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Main Authors: Southam, L, Panoutsopoulou, K, Rayner, N, Chapman, K, Durrant, C, Ferreira, T, Arden, N, Carr, A, Deloukas, P, Doherty, M, Loughlin, J, McCaskie, A, Ollier, W, Ralston, S, Spector, T, Valdes, A, Wallis, G, Wilkinson, J, Marchini, J, Zeggini, E
פורמט: Journal article
שפה:English
יצא לאור: 2011

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