Tapping out a mechanical code for T cell triggering.

Mechanical forces play increasingly recognized roles in T cell receptor (TCR) signal transduction. Hu and Butte (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511053) demonstrate that actin is required for T cells to generate forces at the TCR and that exogenous application of force can emula...

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Bibliographic Details
Main Authors: Dustin, M, Kam, L
Format: Journal article
Language:English
Published: Rockefeller University Press 2016