Tapping out a mechanical code for T cell triggering.
Mechanical forces play increasingly recognized roles in T cell receptor (TCR) signal transduction. Hu and Butte (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511053) demonstrate that actin is required for T cells to generate forces at the TCR and that exogenous application of force can emula...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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Rockefeller University Press
2016
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| _version_ | 1797050656288145408 |
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| author | Dustin, M Kam, L |
| author_facet | Dustin, M Kam, L |
| author_sort | Dustin, M |
| collection | OXFORD |
| description | Mechanical forces play increasingly recognized roles in T cell receptor (TCR) signal transduction. Hu and Butte (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511053) demonstrate that actin is required for T cells to generate forces at the TCR and that exogenous application of force can emulate these cytoskeletal forces and trigger T cell activation. |
| first_indexed | 2024-03-06T18:08:24Z |
| format | Journal article |
| id | oxford-uuid:0231f6fe-0a36-4db1-b0e6-f18c40404025 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:08:24Z |
| publishDate | 2016 |
| publisher | Rockefeller University Press |
| record_format | dspace |
| spelling | oxford-uuid:0231f6fe-0a36-4db1-b0e6-f18c404040252022-03-26T08:39:17ZTapping out a mechanical code for T cell triggering.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:0231f6fe-0a36-4db1-b0e6-f18c40404025EnglishSymplectic Elements at OxfordRockefeller University Press2016Dustin, MKam, LMechanical forces play increasingly recognized roles in T cell receptor (TCR) signal transduction. Hu and Butte (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511053) demonstrate that actin is required for T cells to generate forces at the TCR and that exogenous application of force can emulate these cytoskeletal forces and trigger T cell activation. |
| spellingShingle | Dustin, M Kam, L Tapping out a mechanical code for T cell triggering. |
| title | Tapping out a mechanical code for T cell triggering. |
| title_full | Tapping out a mechanical code for T cell triggering. |
| title_fullStr | Tapping out a mechanical code for T cell triggering. |
| title_full_unstemmed | Tapping out a mechanical code for T cell triggering. |
| title_short | Tapping out a mechanical code for T cell triggering. |
| title_sort | tapping out a mechanical code for t cell triggering |
| work_keys_str_mv | AT dustinm tappingoutamechanicalcodefortcelltriggering AT kaml tappingoutamechanicalcodefortcelltriggering |