Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.

Transcription factors such as Scl/Tal1, Lmo2, and Runx1 are essential for the development of hematopoietic stem cells (HSCs). However, the precise mechanisms by which these factors interact to form transcriptional networks, as well as the identity of the genes downstream of these regulatory cascades...

Full description

Bibliographic Details
Main Authors: Landry, JR, Kinston, S, Knezevic, K, de Bruijn, M, Wilson, N, Nottingham, W, Peitz, M, Edenhofer, F, Pimanda, J, Ottersbach, K, Göttgens, B
Format: Journal article
Language:English
Published: 2008