Active RNA polymerases: mobile or immobile molecular machines?

It is widely assumed that active RNA polymerases track along their templates to produce a transcript. We test this using chromosome conformation capture and human genes switched on rapidly and synchronously by tumour necrosis factor alpha (TNFalpha); one is 221 kbp SAMD4A, which a polymerase takes m...

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Bibliographic Details
Main Authors: Papantonis, A, Larkin, J, Wada, Y, Ohta, Y, Ihara, S, Kodama, T, Cook, P
Format: Journal article
Language:English
Published: 2010