Adenosine release during seizures attenuates GABAA receptor-mediated depolarization.
Seizure-induced release of the neuromodulator adenosine is a potent endogenous anticonvulsant mechanism, which limits the extension of seizures and mediates seizure arrest. For this reason several adenosine-based therapies for epilepsy are currently under development. However, it is not known how ad...
Váldodahkkit: | , , |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
2012
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