11β-Hydroxysteroid dehydrogenase type 1 as a therapeutic target in the metabolic syndrome
The global epidemic of obesity and the metabolic syndrome has focused the need for novel treatments. Here we describe the putative pathogenic role of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), an enzyme that generates active glucocorticoid, cortisol, within liver and adipose tissue. Further...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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