Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques.

A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a multicomponent, multistage DNA vaccine for the simian malaria species Plasmodium knowlesi including...

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Bibliographic Details
Main Authors: Rogers, W, Baird, J, Kumar, A, Tine, J, Weiss, W, Aguiar, J, Gowda, K, Gwadz, R, Kumar, S, Gold, M, Hoffman, S
Format: Journal article
Language:English
Published: 2001