Discovery and characterization of ZUFSP/ZUP1, a distinct deubiquitinase class important for genome stability

<p style="text-align:justify;"> Deubiquitinating enzymes (DUBs) are important regulators of ubiquitin signaling. Here, we report the discovery of deubiquitinating activity in ZUFSP/C6orf113. High-resolution crystal structures of ZUFSP in complex with ubiquitin reveal several distinc...

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Bibliographic Details
Main Authors: Kwasna, D, Rehman, SA, Natarajan, J, Matthews, S, Madden, R, De Cesare, V, Weidlich, S, Virdee, S, Ahel, I, Gibbs-Seymour, I, Kulathu, Y
Format: Journal article
Language:English
Published: Elsevier 2018