Mycolactone-mediated neurite degeneration and functional effects in cultured human and rat DRG neurons: mechanisms underlying hypoalgesia in Buruli ulcer

<strong>Background</strong> Mycolactone is a polyketide toxin secreted by the mycobacterium Mycobacterium ulcerans, responsible for the extensive hypoalgesic skin lesions characteristic of patients with Buruli ulcer. A recent pre-clinical study proposed that mycolactone may produce analg...

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Bibliographic Details
Main Authors: Anand, U, Sinisi, M, Fox, M, Macquillan, A, Quick, T, Korchev, Y, Bountra, C, McCarthy, T, Anand, P
Format: Journal article
Language:English
Published: SAGE Publications 2016