Variable var transition rates underlie antigenic variation in malaria.
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is expressed on the surface of infected erythrocytes where it plays a central role in both infected erythrocytes cytoadhesion and immune evasion. Switches in clonal expression of PfEMP1 result in antigenic variation that facilitates long-...
Autori principali: | , , , , |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2004
|