Three-dimensional structure of phosphorylase kinase at 22 A resolution and its complex with glycogen phosphorylase b.

Phosphorylase kinase (PhK) integrates hormonal and neuronal signals and is a key enzyme in the control of glycogen metabolism. PhK is one of the largest of the protein kinases and is composed of four types of subunit, with stoichiometry (alphabetagammadelta)(4) and a total MW of 1.3 x 10(6). PhK cat...

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Bibliographic Details
Main Authors: Vénien-Bryan, C, Lowe, E, Boisset, N, Traxler, K, Johnson, L, Carlson, G
Format: Journal article
Language:English
Published: 2002