Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) comprising 181,522 cases among 1,165,690 participants of predominantly Europea...

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Bibliografiske detaljer
Main Authors: Aragam, KG, Jiang, T, Goel, A, Kanoni, S, Wolford, BN, Atri, DS, Weeks, EM, Wang, M, Hindy, G, Zhou, W, Grace, C, Roselli, C, Marston, NA, Kamanu, FK, Surakka, I, Venegas, LM, Sherliker, P, Koyama, S, Ishigaki, K, Åsvold, BO, Brown, MR, Brumpton, B, de Vries, PS, Giannakopoulou, O, Giardoglou, P, Gudbjartsson, DF, Güldener, U, Haider, SMI, Helgadottir, A, Ibrahim, M, Kastrati, A, Kessler, T, Kyriakou, T, Konopka, T, Li, L, Ma, L, Meitinger, T, Mucha, S, Munz, M, Murgia, F, Nielsen, JB, Nöthen, MM, Pang, S, Reinberger, T, Schnitzler, G, Smedley, D, Thorleifsson, G, von Scheidt, M, Ulirsch, JC, Biobank Japan, Hopewell, JC, Clarke, R, Watkins, H
Andre forfattere: The CARDIoGRAMplusC4D Consortium
Format: Journal article
Sprog:English
Udgivet: Springer Nature 2022

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