Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells
<p>Semi-invariant natural killer T (iNKT) cells are self-reactive lymphocytes, yet how this lineage attains self-tolerance remains unknown. iNKT cells constitutively express high levels of <em>Nr4a1</em>-encoded Nur77, a transcription factor that integrates signal strength...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
National Academy of Sciences
2020
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