Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells

Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells

<p>Semi-invariant natural killer T (iNKT) cells are self-reactive lymphocytes, yet how this lineage attains self-tolerance remains unknown. iNKT cells constitutively express high levels of <em>Nr4a1</em>-encoded Nur77, a transcription factor that integrates signal strength...

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Bibliographic Details
Main Authors:	Kumar, A, Hill, TM, Gordy, LE, Suryadevara, N, Wu, L, Flyak, AI, Bezbradica, JS, Van Kaer, L, Joyce, S
Format:	Journal article
Language:	English
Published:	National Academy of Sciences 2020

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