Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells
<p>Semi-invariant natural killer T (iNKT) cells are self-reactive lymphocytes, yet how this lineage attains self-tolerance remains unknown. iNKT cells constitutively express high levels of <em>Nr4a1</em>-encoded Nur77, a transcription factor that integrates signal strength...
| Main Authors: | , , , , , , , , |
|---|---|
| פורמט: | Journal article |
| שפה: | English |
| יצא לאור: |
National Academy of Sciences
2020
|