Lipid-dependent regulation of ion channels and GPCRs: insights from structures and simulations
Ion channels and GPCRs are regulated by lipids in their membrane environment. Structural studies combined with biophysical and molecular simulation investigations reveal interaction sites for specific lipids on membrane protein structures. For K channels, PIP2 plays a key role in regulation of Kv an...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Annual Reviews
2019
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