Common coding variant in SERPINA1 increases the risk for large artery stroke

Large artery atherosclerotic stroke (LAS) shows substantial heritability not explained by previous genome-wide association studies. Here, we explore the role of coding variation in LAS by analyzing variants on the HumanExome BeadChip in a total of 3,127 cases and 9,778 controls from Europe, Australi...

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Bibliographic Details
Main Authors:	Malik, R, Dau, T, Gonik, M, Sivakumar, A, Deredge, D, Edeleva, E, Götzfried, J, Van Der Laan, S, Pasterkamp, G, Beaufort, N, Seixas, S, Bevan, S, Lincz, L, Holliday, E, Burgess, A, Rannikmäe, K, Minnerup, J, Kriebel, J, Waldenberger, M, Müller-Nurasyid, M, Lichtner, P, Saleheen, D, International Stroke Genetics Consortium, Rothwell, P, Levi, C, Attia, J, Sudlow, C, Braun, D, Markus, H, Wintrode, P, Berger, K, Jenne, D, Dichgans, M
Format:	Journal article
Language:	English
Published:	National Academy of Sciences 2017

Common coding variant in SERPINA1 increases the risk for large artery stroke

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