Phenotypic switching mechanisms determine the structure of cell migration into extracellular matrix under the ‘go-or-grow’ hypothesis

A fundamental feature of collective cell migration is phenotypic heterogeneity which, for example, influences tumour progression and relapse. While current mathematical models often consider discrete phenotypic structuring of the cell population, in-line with the ‘go-or-grow’ hypothesis [1, 2], they...

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Bibliographic Details
Main Authors: Crossley, R, Painter, K, Lorenzi, T, Maini, P, Baker, R
Format: Journal article
Language:English
Published: Elsevier 2024