Functional analysis of the influenza virus H5N1 nucleoprotein tail loop reveals amino acids that are crucial for oligomerization and ribonucleoprotein activities.

Homo-oligomerization of the nucleoprotein (NP) of influenza A virus is crucial for providing a major structural framework for the assembly of viral ribonucleoprotein (RNP) particles. The nucleoprotein is also essential for transcription and replication during the virus life cycle. In the H5N1 NP str...

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Bibliographic Details
Main Authors: Chan, W, Ng, A, Robb, N, Lam, M, Chan, P, Au, S, Wang, J, Fodor, E, Shaw, P
Format: Journal article
Language:English
Published: 2010