The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors.

Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ from canonical 7TM receptors. Despite their essential roles in immunity, tumorigenesis, and development, the mechanisms of aGPCR...

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Bibliographic Details
Main Authors: Prömel, S, Frickenhaus, M, Hughes, S, Mestek, L, Staunton, D, Woollard, A, Vakonakis, I, Schöneberg, T, Schnabel, R, Russ, A, Langenhan, T
Format: Journal article
Language:English
Published: 2012