The GPS motif is a molecular switch for bimodal activities of adhesion class G protein-coupled receptors.
Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ from canonical 7TM receptors. Despite their essential roles in immunity, tumorigenesis, and development, the mechanisms of aGPCR...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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