Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

We investigated the role of the T cell antigen receptor (TcR) in control of T cell migration in an in vitro system. We used T cells from transgenic mice bearing a TcR for the lysozyme peptide 48-62 bound to I-A(k) (3A9). T cells from the 3A9 TcR transgenic mice crawled on purified intercellular adhe...

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Bibliographic Details
Main Authors: Dustin, M, Bromley, S, Kan, Z, Peterson, D, Unanue, E
Format: Journal article
Language:English
Published: 1997