Molecular pathology shows p16 methylation in nonadenomatous pituitaries from patients with Cushing's disease.
PURPOSE: The majority of cases of Cushing's disease are due to the presence of a corticotroph microadenoma. Less frequently no adenoma is found and histology shows either corticotroph hyperplasia, or apparently normal pituitary. In this study we have used molecular pathology to determine wheth...
Principais autores: | Simpson, D, McNicol, A, Murray, D, Bahar, A, Turner, H, Wass, J, Esiri, M, Clayton, R, Farrell, W |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2004
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