D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo.

We identify Drosophila TACC (D-TACC) as a novel protein that is concentrated at centrosomes and interacts with microtubules. We show that D-TACC is essential for normal spindle function in the early embryo; if D-TACC function is perturbed by mutation or antibody injection, the microtubules emanating...

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Bibliographic Details
Main Authors: Gergely, F, Kidd, D, Jeffers, K, Wakefield, J, Raff, J
Format: Journal article
Language:English
Published: 2000