Short-chain dehydrogenases/reductases (SDR): the 2002 update.

Short-chain dehydrogenases/reductases (SDR): the 2002 update.

Short-chain dehydrogenases/reductases (SDR) form a large, functionally heterogeneous protein family presently with about 3000 primary and about 30 3D structures deposited in databases. Despite low sequence identities between different forms (about 15-30%), the 3D structures display highly similar al...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Oppermann, U, Filling, C, Hult, M, Shafqat, N, Wu, X, Lindh, M, Shafqat, J, Nordling, E, Kallberg, Y, Persson, B, Jörnvall, H
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2003

Gelijkaardige items

Short-chain dehydrogenase/reductase (SDR) relationships: a large family with eight clusters common to human, animal, and plant genomes.
door: Kallberg, Y, et al.
Gepubliceerd in: (2002)

Short-chain dehydrogenases/reductases (SDRs).
door: Kallberg, Y, et al.
Gepubliceerd in: (2002)

Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases.
door: Filling, C, et al.
Gepubliceerd in: (2001)

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.
door: Persson, B, et al.
Gepubliceerd in: (2009)

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.
door: Persson, B, et al.
Gepubliceerd in: (2009)

Structure-function relationships of SDR hydroxysteroid dehydrogenases.
door: Oppermann, U, et al.
Gepubliceerd in: (1997)

Coenzyme-based functional assignments of short-chain dehydrogenases/reductases (SDRs).
door: Persson, B, et al.
Gepubliceerd in: (2003)

Critical residues for structure and catalysis in short-chain dehydrogenases/reductases.
door: Filling, C, et al.
Gepubliceerd in: (2002)

Structural role of conserved Asn179 in the short-chain dehydrogenase/reductase scaffold.
door: Filling, C, et al.
Gepubliceerd in: (2001)

Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes.
door: Kavanagh, K, et al.
Gepubliceerd in: (2008)

Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes.
door: Kavanagh, K, et al.
Gepubliceerd in: (2008)

The human short-chain dehydrogenase/reductase (SDR) superfamily: a bioinformatics summary
door: Bray, J, et al.
Gepubliceerd in: (2009)

The human short-chain dehydrogenase/reductase (SDR) superfamily: a bioinformatics summary.
door: Bray, J, et al.
Gepubliceerd in: (2009)

Active site directed mutagenesis of 3 beta/17 beta-hydroxysteroid dehydrogenase establishes differential effects on short-chain dehydrogenase/reductase reactions.
door: Oppermann, U, et al.
Gepubliceerd in: (1997)

Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models
door: Kallberg, Y, et al.
Gepubliceerd in: (2010)

Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models.
door: Kallberg, Y, et al.
Gepubliceerd in: (2010)

Bioinformatics in studies of SDR and MDR enzymes.
door: Persson, B, et al.
Gepubliceerd in: (1999)

Forms and functions of human SDR enzymes.
door: Oppermann, U, et al.
Gepubliceerd in: (2001)

Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue.
door: Shafqat, N, et al.
Gepubliceerd in: (2006)

The Plant Short-Chain Dehydrogenase (SDR) superfamily: genome-wide inventory and diversification patterns
door: Moummou Hanane, et al.
Gepubliceerd in: (2012-11-01)

Regulatory factors and motifs in SDR enzymes.
door: Oppermann, U, et al.
Gepubliceerd in: (1999)

Structure-function relationships of 3 beta-hydroxysteroid dehydrogenases involved in bile acid metabolism.
door: Filling, C, et al.
Gepubliceerd in: (1999)

Role of short-chain hydroxyacyl CoA dehydrogenases in SCHAD deficiency.
door: Filling, C, et al.
Gepubliceerd in: (2008)

An ethanol-inducible MDR ethanol dehydrogenase/acetaldehyde reductase in Escherichia coli: structural and enzymatic relationships to the eukaryotic protein forms.
door: Shafqat, J, et al.
Gepubliceerd in: (1999)

Human and rodent type 1 11beta-hydroxysteroid dehydrogenases are 7beta-hydroxycholesterol dehydrogenases involved in oxysterol metabolism.
door: Hult, M, et al.
Gepubliceerd in: (2004)

Biochemical characterization of TASSELSEED 2, an essential plant short-chain dehydrogenase/reductase with broad spectrum activities.
door: Wu, X, et al.
Gepubliceerd in: (2007)

Human type 10 17 beta-hydroxysteroid dehydrogenase: molecular modelling and substrate docking.
door: Nordling, E, et al.
Gepubliceerd in: (2001)

Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement
door: Persson Bengt, et al.
Gepubliceerd in: (2010-10-01)

Expanded substrate screenings of human and Drosophila type 10 17beta-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3alpha/7alpha/7beta/17beta/20beta/21-HSD.
door: Shafqat, N, et al.
Gepubliceerd in: (2003)

Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.
door: Stambergova, H, et al.
Gepubliceerd in: (2014)

Crystallographic structure determination and analysis of a potential short-chain dehydrogenase/reductase (SDR) from multi-drug resistant Acinetobacter baumannii.
door: Seyed Mohammad Ghafoori, et al.
Gepubliceerd in: (2023-01-01)

Crystallographic structure determination and analysis of a potential short-chain dehydrogenase/reductase (SDR) from multi-drug resistant Acinetobacter baumannii
door: Seyed Mohammad Ghafoori, et al.
Gepubliceerd in: (2023-01-01)

Selective inhibition of human type 1 11beta-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics.
door: Hult, M, et al.
Gepubliceerd in: (1998)

Studies on variants of alcohol dehydrogenases and its domains.
door: Shafqat, J, et al.
Gepubliceerd in: (1999)

Comparative enzymology of 11 beta -hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (Guinea pig) versus sensitive (human) species.
door: Shafqat, N, et al.
Gepubliceerd in: (2003)

Human liver class I alcohol dehydrogenase gammagamma isozyme: the sole cytosolic 3beta-hydroxysteroid dehydrogenase of iso bile acids.
door: Marschall, H, et al.
Gepubliceerd in: (2000)

Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease.
door: Oppermann, U, et al.
Gepubliceerd in: (1999)

Genome-wide identification of short-chain dehydrogenases/reductases genes and functional characterization of ApSDR53C2 in melanin biosynthesis in Arthrinium phaeospermum
door: Jiao Liao, et al.
Gepubliceerd in: (2025-01-01)

Molecular cloning and sequencing of mouse hepatic 11 beta-hydroxysteroid dehydrogenase/carbonyl reductase. A member of the short chain dehydrogenase superfamily.
door: Maser, E, et al.
Gepubliceerd in: (1995)

Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities.
door: Jörnvall, H, et al.
Gepubliceerd in: (2010)