The antigen dose determines T helper subset development by regulation of CD40 ligand.
Although the amount of antigen and the strength of T cell stimulation have been suggested to regulate Th1 vs. Th2 polarization, it remains unclear how the antigen dose and the strength of signal is detected by the T cell and translated into differential cytokine production. Using co-cultures of dend...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2000
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