Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP

Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP

The new and growing family of interleukin-1β-converting enzyme (ICE) cysteine proteases are now recognised to be major effectors of cellular death by apoptosis. Like other members of this family, the CPP32/Yama proform is activated by processing to its active heterodimeric enzyme or apopain when it...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors:	An, S, Knox, K
Andre forfattere:	Federation of European Biochemical Societies
Format:	Journal article
Sprog:	English
Udgivet:	Elsevier 1996
Fag:	Biochemistry

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