Molecular mechanism of BMP signal control by Twisted gastrulation
Twisted gastrulation (TWSG1) is an evolutionarily conserved secreted glycoprotein which controls signaling by Bone Morphogenetic Proteins (BMPs). TWSG1 binds BMPs and their antagonist Chordin to control BMP signaling during embryonic development, kidney regeneration and cancer. We report crystal str...
Main Authors: | Malinauskas, T, Moore, G, Rudolf, AF, Eggington, H, Belnoue-Davis, HL, El Omari, K, Griffiths, SC, Woolley, RE, Duman, R, Wagner, A, Leedham, SJ, Baldock, C, Ashe, HL, Siebold, C |
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Format: | Journal article |
Language: | English |
Published: |
Nature Research
2024
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