Case report: Embedding "digital chronotherapy" into medical devices -- A canine validation for controlling status epilepticus through multi-scale rhythmic brain stimulation

Circadian and other physiological rhythms play a key role in both normal homeostasis and disease processes. Such is the case of circadian and infradian seizure patterns observed in epilepsy. However, these rhythms are not fully exploited in the design of active implantable medical devices. In this p...

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Bibliographic Details
Main Authors: Zamora, M, Meller, S, Kajin, F, Sermon, JJ, Toth, R, Benjaber, M, Dijk, D-J, Bogacz, R, Worrell, GA, Valentin, A, Duchet, B, Volk, HA, Denison, T
Format: Journal article
Language:English
Published: Frontiers Media 2021