Case report: Embedding "digital chronotherapy" into medical devices -- A canine validation for controlling status epilepticus through multi-scale rhythmic brain stimulation
Circadian and other physiological rhythms play a key role in both normal homeostasis and disease processes. Such is the case of circadian and infradian seizure patterns observed in epilepsy. However, these rhythms are not fully exploited in the design of active implantable medical devices. In this p...
Main Authors: | Zamora, M, Meller, S, Kajin, F, Sermon, JJ, Toth, R, Benjaber, M, Dijk, D-J, Bogacz, R, Worrell, GA, Valentin, A, Duchet, B, Volk, HA, Denison, T |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media
2021
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