BRAF and NRAS locus-specific variants have different outcomes on survival to colorectal cancer

Purpose: Somatic mutation status at KRAS, BRAF, and NRAS is associated with prognosis in patients with advanced colorectal cancer (aCRC); however, it remains unclear whether there are intralocus, variant-specific differences in survival and other clinicopathologic parameters.Experimental Design: We...

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Bibliographic Details
Main Authors: Summers, MG, Smith, CG, Maughan, TS, Kaplan, R, Escott-Price, V, Cheadle, JP
Format: Journal article
Language:English
Published: American Association for Cancer Research 2016