Mapping cis- and trans-regulatory effects across multiple tissues in twins.
Sequence-based variation in gene expression is a key driver of disease risk. Common variants regulating expression in cis have been mapped in many expression quantitative trait locus (eQTL) studies, typically in single tissues from unrelated individuals. Here, we present a comprehensive analysis of...
Prif Awduron: | Grundberg, E, Small, K, Hedman, Å, Nica, A, Buil, A, Keildson, S, Bell, J, Yang, T, Meduri, E, Barrett, A, Nisbett, J, Sekowska, M, Wilk, A, Shin, S, Glass, D, Travers, M, Min, J, Ring, S, Ho, K, Thorleifsson, G, Kong, A, Thorsteindottir, U, Ainali, C, Dimas, A, Hassanali, N |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2012
|
Eitemau Tebyg
-
Mapping cis-and trans-regulatory effects across multiple tissues in twins
gan: Grundberg, E, et al.
Cyhoeddwyd: (2012) -
Global analysis of dna methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
gan: Grundberg, E, et al.
Cyhoeddwyd: (2013) -
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.
gan: Grundberg, E, et al.
Cyhoeddwyd: (2013) -
Biomarkers of skin ageing using genome wide transcriptomics
gan: Glass, D, et al.
Cyhoeddwyd: (2011) -
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
gan: Small, K, et al.
Cyhoeddwyd: (2011)