Mapping cis- and trans-regulatory effects across multiple tissues in twins.
Sequence-based variation in gene expression is a key driver of disease risk. Common variants regulating expression in cis have been mapped in many expression quantitative trait locus (eQTL) studies, typically in single tissues from unrelated individuals. Here, we present a comprehensive analysis of...
Հիմնական հեղինակներ: | Grundberg, E, Small, K, Hedman, Å, Nica, A, Buil, A, Keildson, S, Bell, J, Yang, T, Meduri, E, Barrett, A, Nisbett, J, Sekowska, M, Wilk, A, Shin, S, Glass, D, Travers, M, Min, J, Ring, S, Ho, K, Thorleifsson, G, Kong, A, Thorsteindottir, U, Ainali, C, Dimas, A, Hassanali, N |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2012
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Նմանատիպ նյութեր
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Mapping cis-and trans-regulatory effects across multiple tissues in twins
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Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.
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