Mapping cis- and trans-regulatory effects across multiple tissues in twins.
Sequence-based variation in gene expression is a key driver of disease risk. Common variants regulating expression in cis have been mapped in many expression quantitative trait locus (eQTL) studies, typically in single tissues from unrelated individuals. Here, we present a comprehensive analysis of...
Main Authors: | Grundberg, E, Small, K, Hedman, Å, Nica, A, Buil, A, Keildson, S, Bell, J, Yang, T, Meduri, E, Barrett, A, Nisbett, J, Sekowska, M, Wilk, A, Shin, S, Glass, D, Travers, M, Min, J, Ring, S, Ho, K, Thorleifsson, G, Kong, A, Thorsteindottir, U, Ainali, C, Dimas, A, Hassanali, N |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2012
|
Registos relacionados
-
Mapping cis-and trans-regulatory effects across multiple tissues in twins
Por: Grundberg, E, et al.
Publicado em: (2012) -
Global analysis of dna methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements
Por: Grundberg, E, et al.
Publicado em: (2013) -
Global analysis of DNA methylation variation in adipose tissue from twins reveals links to disease-associated variants in distal regulatory elements.
Por: Grundberg, E, et al.
Publicado em: (2013) -
Biomarkers of skin ageing using genome wide transcriptomics
Por: Glass, D, et al.
Publicado em: (2011) -
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
Por: Small, K, et al.
Publicado em: (2011)