Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.
CD8+ cytotoxic T lymphocytes (CTLs) play an important role in containment of virus replication in primary human immunodeficiency virus (HIV) infection. HIV's ability to mutate to escape from CTL pressure is increasingly recognized; but comprehensive studies of escape from the CD8 T cell respons...
Main Authors: | Jones, N, Wei, X, Flower, DR, Wong, M, Michor, F, Saag, MS, Hahn, B, Nowak, M, Shaw, G, Borrow, P |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2004
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