Haplotype estimation for biobank-scale data sets

The UK Biobank (UKB) has recently released genotypes on 152,328 individuals together with extensive phenotypic and lifestyle information. We present a new phasing method, SHAPEIT3, that can handle such biobank-scale data sets and results in switch error rates as low as ∼0.3%. The method exhibits O(N...

Full description

Bibliographic Details
Main Authors: O'Connell, J, Sharp, K, Shrine, N, Wain, L, Hall, I, Tobin, M, Zagury, J, Delaneau, O, Marchini, J
Format: Journal article
Language:English
Published: Nature Publishing Group 2016