Haplotype estimation for biobank-scale data sets
The UK Biobank (UKB) has recently released genotypes on 152,328 individuals together with extensive phenotypic and lifestyle information. We present a new phasing method, SHAPEIT3, that can handle such biobank-scale data sets and results in switch error rates as low as ∼0.3%. The method exhibits O(N...
Main Authors: | O'Connell, J, Sharp, K, Shrine, N, Wain, L, Hall, I, Tobin, M, Zagury, J, Delaneau, O, Marchini, J |
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Format: | Journal article |
Language: | English |
Published: |
Nature Publishing Group
2016
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